Nociceptin (1-7) acetate
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Nociceptin (1-7) acetate

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Nociceptin (1-7) acetate is a potent opioid receptor-like 1 (ORL1) receptor agonist, which in combination with nociceptin can reduce hyperalgesia and has antinociceptive activity.

Category
Peptide Inhibitors
Catalog number
BAT-016337
Molecular Formula
C31H41N7O9
Molecular Weight
655.70
Nociceptin (1-7) acetate
IUPAC Name
acetic acid;(2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]propanoic acid
Synonyms
L-Alanine, N-[N-[N-[N-[N-(N-L-phenylalanylglycyl)glycyl]-L-phenylalanyl]-L-threonyl]glycyl]-, acetate; L-Phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanine acetate; 1-7-Orphanin FQ (pig) acetate; H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-OH.CH3CO2H
Related CAS
178249-42-8 (free base)
Purity
≥95%
Sequence
FGGFTGA.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in DMSO
InChI
InChI=1S/C31H41N7O9.C2H4O2/c1-18(31(46)47)36-25(41)17-35-30(45)27(19(2)39)38-29(44)23(14-21-11-7-4-8-12-21)37-26(42)16-33-24(40)15-34-28(43)22(32)13-20-9-5-3-6-10-20;1-2(3)4/h3-12,18-19,22-23,27,39H,13-17,32H2,1-2H3,(H,33,40)(H,34,43)(H,35,45)(H,36,41)(H,37,42)(H,38,44)(H,46,47);1H3,(H,3,4)/t18-,19+,22-,23-,27-;/m0./s1
InChI Key
PQICXRUORNELKS-SIJKDDLCSA-N
Canonical SMILES
CC(C(C(=O)NCC(=O)NC(C)C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=CC=C2)N)O.CC(=O)O
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