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Application Area

Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

The pentapeptide TRSAW is a potent inhibitor of osteoclastic bone resorption in vitro.

Category

Peptide Inhibitors

Catalog number

BAT-015912

CAS number

138949-73-2

Molecular Formula

C27H41N9O8

Molecular Weight

619.67

Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat)

Specification

IUPAC Name

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid

Synonyms

(6S,9S,12S,15S)-15-((1H-indol-3-yl)methyl)-1-amino-6-((2S,3R)-2-amino-3-hydroxybutanamido)-9-(hydroxymethyl)-1-imino-12-methyl-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid; pTH-rP (107-111) (human, bovine, dog, horse, mouse, rabbit, rat)

Sequence

H-Thr-Arg-Ser-Ala-Trp-OH

Storage

Store at -20°C

InChI

InChI=1S/C27H41N9O8/c1-13(22(39)35-19(26(43)44)10-15-11-32-17-7-4-3-6-16(15)17)33-24(41)20(12-37)36-23(40)18(8-5-9-31-27(29)30)34-25(42)21(28)14(2)38/h3-4,6-7,11,13-14,18-21,32,37-38H,5,8-10,12,28H2,1-2H3,(H,33,41)(H,34,42)(H,35,39)(H,36,40)(H,43,44)(H4,29,30,31)/t13-,14+,18-,19-,20-,21-/m0/s1

InChI Key

FFEMNOZDYSNTNO-TWGJCYIBSA-N

Canonical SMILES

CC(C(C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)N)O