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PAR-4 Agonist Peptide, amide TFA

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

PAR-4 Agonist Peptide, amide TFA is a proteinase-activated receptor-4 (PAR-4) agonist. It has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.

Category

Peptide Inhibitors

Catalog number

BAT-009121

CAS number

1228078-65-6

Molecular Formula

C36H49F3N8O9

Molecular Weight

794.82

Specification

IUPAC Name

(2S)-N-[2-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]-1-[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid

Synonyms

PAR-4-AP TFA; AY-NH2 TFA; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide,trifluoroacetate salt

Related CAS

352017-71-1 (free base)

Purity

99%

Sequence

Ala-Tyr-Pro-Gly-Lys-Phe

Storage

Store at -20°C

InChI

InChI=1S/C34H48N8O7.C2HF3O2/c1-21(36)31(46)41-27(19-23-12-14-24(43)15-13-23)34(49)42-17-7-11-28(42)33(48)38-20-29(44)39-25(10-5-6-16-35)32(47)40-26(30(37)45)18-22-8-3-2-4-9-22;3-2(4,5)1(6)7/h2-4,8-9,12-15,21,25-28,43H,5-7,10-11,16-20,35-36H2,1H3,(H2,37,45)(H,38,48)(H,39,44)(H,40,47)(H,41,46);(H,6,7)/t21-,25-,26-,27-,28-;/m0./s1

InChI Key

BGPJLFVICWHITH-HKJXYENISA-N

Canonical SMILES

CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N2CCCC2C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)N)N.C(=O)(C(F)(F)F)O