1.Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer.
Huss L1, Butt S, Borgquist S, Almquist M, Malm J, Manjer J. Cancer Causes Control. 2014 Sep;25(9):1131-40. doi: 10.1007/s10552-014-0413-3. Epub 2014 Jun 22.
PURPOSE: Vitamin D, parathyroid hormone (PTH) and calcium in blood are correlated with each other. Previous studies have suggested vitamin D to have anti-proliferative effects on tumor cells, whereas PTH may have carcinogenic effects. A cancer disease may influence calcium levels in blood, but less is known about calcium and its potential effect on cancer risk and survival. The aim of this study was to examine pre-diagnostic levels of vitamin D (25OHD), PTH and calcium in relation to survival after breast cancer.
2.The third/second generation PTH assay ratio as a marker for parathyroid carcinoma: evaluation using an automated platform.
Cavalier E1, Betea D, Schleck ML, Gadisseur R, Vroonen L, Delanaye P, Daly AF, Beckers A. J Clin Endocrinol Metab. 2014 Mar;99(3):E453-7. doi: 10.1210/jc.2013-3730. Epub 2013 Jan 1.
BACKGROUND: Parathyroid carcinoma (PCa) is rare and often difficult to differentiate initially from benign disease. Because PCa oversecretes amino PTH that is detected by third-generation but not by second-generation PTH assays, the normal 3rd/2nd generation PTH ratio (<1) is inverted in PCa (ie, >1).
3.Comparative mortality-predictability using alkaline phosphatase and parathyroid hormone in patients on peritoneal dialysis and hemodialysis.
Rhee CM1, Molnar MZ1, Lau WL2, Ravel V3, Kovesdy CP2, Mehrotra R3, Kalantar-Zadeh K1. Perit Dial Int. 2014 Nov-Dec;34(7):732-48. doi: 10.3747/pdi.2013.00110. Epub 2014 Jan 2.
BACKGROUND: In hemodialysis (HD) patients, serum alkaline phosphatase (ALP) and parathyroid hormone (PTH) derangements are associated with mortality, but outcome-predictability using ALP and PTH in peritoneal dialysis (PD) patients remains uncertain.
4.Association of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone with mortality among middle-aged and older European men.
Lee DM1, Vanderschueren D2, Boonen S3, O'Neill TW4, Pendleton N5, Pye SR4, Ravindrarajah R6, Gielen E3, Claessens F7, Bartfai G8, Casanueva FF9, Finn JD6, Forti G10, Giwercman A11, Han TS12, Huhtaniemi IT13, Kula K14, Lean ME15, Punab M16, Wu FC6; Europea Age Ageing. 2014 Jul;43(4):528-35. doi: 10.1093/ageing/aft206. Epub 2013 Dec 26.
BACKGROUND: vitamin D deficiency has been associated with an increased risk of mortality, but whether this relationship is causal or linked to co-existent comorbidity and adverse life factors remains uncertain. Our objective was to determine whether endogenous 25-hydroxyvitamin D (25(OH)D), 1,25-dihydroxyvitamin D (1,25(OH)2D) and parathyroid hormone (PTH) levels predicted all-cause, cardiovascular and cancer mortality independently of health and lifestyle factors.
