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Parkerin

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Parkerin is an antimicrobial peptide found in Nanorana parkeri (Xizang plateau frog), and has antimicrobial activity against gram-positive bacterium S. aureus, Enterococcus faecium and gram-negative bacterium Acinetobacter baumannii (MIC=37.5 µg/ml) and fungus C. albicans.

Category
Functional Peptides
Catalog number
BAT-011609
Molecular Formula
C85H141N25O25S
Molecular Weight
1945.27
IUPAC Name
glycyl-L-tryptophyl-L-alanyl-L-asparaginyl-L-threonyl-L-leucyl-L-lysyl-L-asparaginyl-L-valyl-L-alanylglycylglycyl-L-leucyl-L-cysteinyl-L-lysyl-L-isoleucyl-L-threonylglycyl-L-alanyl-L-alanine
Synonyms
Gly-Trp-Ala-Asn-Thr-Leu-Lys-Asn-Val-Ala-Gly-Gly-Leu-Cys-Lys-Ile-Thr-Gly-Ala-Ala
Appearance
Powder
Purity
≥97%
Sequence
GWANTLKNVAGGLCKITGAA
Storage
Store at -20°C
1. Rickettsiosis Caused by Rickettsia parkeri, Mexico
Gaspar Peniche-Lara, Victor Lara-Perera Emerg Infect Dis. 2022 Feb;28(2):478-479. doi: 10.3201/eid2802.210454.
We report a human case of rickettsiosis caused by Rickettsia parkeri strain Atlantic Rainforest in Mexico in an adult woman from a small town in the north of Yucatan, Mexico. We confirmed diagnosis using conventional PCR and sequence analysis. Health providers should be aware of clinical manifestations of rickettsioses in this region.
2. Molecular confirmation of Rickettsia parkeri in humans from Southern Mexico
Marco Torres-Castro, Sokani Sánchez-Montes, Pablo Colunga-Salas, Henry Noh-Pech, Enrique Reyes-Novelo, Roger I Rodríguez-Vivas Zoonoses Public Health. 2022 Jun;69(4):382-386. doi: 10.1111/zph.12927. Epub 2022 Feb 9.
Human tick-borne rickettsioses are caused by Rickettsia africae, Rickettsia massiliae, Rickettsia parkeri, Rickettsia philipi and Rickettsia rickettsii in the American continent. Rickettsia parkeri represents the second most important agent of eschar-associated spotted fever throughout the American continent. In Mexico, the presence of three strains of this bacterium (Black Gap, Maculatum and Atlantic Rainforest) has recently been reported in four species of ticks from five states (Baja California, Campeche, Sonora, Tabasco and Veracruz) and rickettsaemia was demonstrated in a dog from the state of Yucatán. We report two human cases of R. parkeri-rickettsiosis from Yucatan, Mexico. These findings have increased the interest in R. parkeri surveillance in the human population, due to the fluctuating regional Spotted Fever morbidity and mortality in the country.
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