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The peptide PCLUS3-18IIIB consists of the multideterminant helper segment PCLUS3 (KQIINMWQEVGKAMYAPPISGQIR), derived from the CD4 binding domain of HIV-1 IIIB, combined with the immunodominant CTL epitope presented by H-2Dd in BALB/c mice, called P18 IIIB (RIQRGPGRAFVTIGK), derived from the V3 loop of the IIIB strain of HIV-1, in a single continuous peptide.
