Pep2m, myristoylated acetate
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Pep2m, myristoylated acetate

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Pep2m, myristoylated acetate, a cell-permeable myristoylated form of pep2m, is a peptide inhibitor of the GluA2 subunit binding to NSF, reducing postsynaptic currents in CA1 neurons, AMPA-mediated hippocampal neuron currents, and AMPA receptor surface expression.

Category
Peptide Inhibitors
Catalog number
BAT-016391
Molecular Formula
C65H122N18O16S
Molecular Weight
1443.86
Pep2m, myristoylated acetate
IUPAC Name
acetic acid;(2S)-5-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-(tetradecanoylamino)hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]hexanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-5-oxopentanoic acid
Synonyms
Myr-pep2m acetate; myristoyl-Lys-Arg-Met-Lys-Val-Ala-Lys-Asn-Ala-Gln-OH.CH3CO2H; N-myristoyl-L-lysyl-L-arginyl-L-methionyl-L-lysyl-L-valyl-L-alanyl-L-lysyl-L-asparagyl-L-alanyl-L-glutamine acetate
Related CAS
1423381-07-0 (free base)
Purity
≥95%
Sequence
Myr-KRMKVAKNAQ.CH3CO2H
Storage
Store at -20°C
InChI
InChI=1S/C63H118N18O14S.C2H4O2/c1-7-8-9-10-11-12-13-14-15-16-17-29-51(84)74-42(25-18-21-33-64)55(87)77-45(28-24-36-71-63(69)70)56(88)78-46(32-37-96-6)58(90)76-44(27-20-23-35-66)59(91)81-52(39(2)3)61(93)73-41(5)53(85)75-43(26-19-22-34-65)57(89)80-48(38-50(68)83)60(92)72-40(4)54(86)79-47(62(94)95)30-31-49(67)82;1-2(3)4/h39-48,52H,7-38,64-66H2,1-6H3,(H2,67,82)(H2,68,83)(H,72,92)(H,73,93)(H,74,84)(H,75,85)(H,76,90)(H,77,87)(H,78,88)(H,79,86)(H,80,89)(H,81,91)(H,94,95)(H4,69,70,71);1H3,(H,3,4)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,52-;/m0./s1
InChI Key
XUWBHAVHQKNSJU-HVXFLXQCSA-N
Canonical SMILES
CCCCCCCCCCCCCC(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)O.CC(=O)O
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