[(pF)Phe4]Nociceptin(1-13)NH2 acetate
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[(pF)Phe4]Nociceptin(1-13)NH2 acetate

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[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a highly potent and selective nociceptin/orphanin FQ receptor (OP4) agonist peptide. It has relatively long lasting pronociceptive, hypotensive, negative inotropic and feeding stimulation effects in vivo.

Category
Peptide Inhibitors
Catalog number
BAT-016454
Molecular Formula
C63H103FN22O17
Molecular Weight
1459.63
[(pF)Phe4]Nociceptin(1-13)NH2 acetate
IUPAC Name
acetic acid;(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]acetyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanamide
Appearance
Solid
Purity
98%
Storage
Store at -20°C
InChI
InChI=1S/C61H99FN22O15.C2H4O2/c1-33(76-47(88)31-75-59(99)49(35(3)86)84-57(97)44(28-37-19-21-38(62)22-20-37)78-48(89)30-73-46(87)29-74-53(93)39(65)27-36-13-5-4-6-14-36)51(91)80-43(18-12-26-72-61(69)70)55(95)82-41(16-8-10-24-64)56(96)83-45(32-85)58(98)77-34(2)52(92)81-42(17-11-25-71-60(67)68)54(94)79-40(50(66)90)15-7-9-23-63;1-2(3)4/h4-6,13-14,19-22,33-35,39-45,49,85-86H,7-12,15-18,23-32,63-65H2,1-3H3,(H2,66,90)(H,73,87)(H,74,93)(H,75,99)(H,76,88)(H,77,98)(H,78,89)(H,79,94)(H,80,91)(H,81,92)(H,82,95)(H,83,96)(H,84,97)(H4,67,68,71)(H4,69,70,72);1H3,(H,3,4)/t33-,34-,35+,39-,40-,41-,42-,43-,44-,45-,49-;/m0./s1
InChI Key
SNUVGBPYIHBTCC-ZEEIVWDVSA-N
Canonical SMILES
CC(C(C(=O)NCC(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC1=CC=C(C=C1)F)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=CC=C2)N)O.CC(=O)O
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