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Pleurain-a1

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Pleurain-a1 is an antimicrobial peptide found in Rana pleuraden (Yunnan pond frog, Babina pleuraden), and has antibacterial activity against gram-negative bacteria Escherichia coli, Helicobacter pylori NCTC 11637 (MIC=30 µg/ml) and gram-positive bacteria Bacillus dysenteriae (MIC=120 µg/ml), Staphylococcus aureus, and has anti-yeast activity against Candida albicans.

Category
Functional Peptides
Catalog number
BAT-011513
Molecular Formula
C136H224N36O37S3
Molecular Weight
3051.68
IUPAC Name
(4R,7S,10S,13S,16S,19S,22R)-22-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-2-((S)-2-((S)-1-(L-seryl-L-isoleucyl-L-isoleucyl-L-threonyl-L-methionyl-L-threonyl-L-lysyl-L-glutamyl-L-alanyl-L-lysyl-L-leucyl)pyrrolidine-2-carboxamido)-5-amino-5-oxopentanamido)-4-methylpentanamido)-3-(1H-indol-3-yl)propanamido)-6-aminohexanamido)-5-amino-5-oxopentanamido)-3-methylpentanamido)propanamido)-10-(2-amino-2-oxoethyl)-19-(3-guanidinopropyl)-13-(4-hydroxybenzyl)-7-((R)-1-hydroxyethyl)-16-isobutyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxylic acid
Synonyms
Pleurain A1; Ser-Ile-Ile-Thr-Met-Thr-Lys-Glu-Ala-Lys-Leu-Pro-Gln-Leu-Trp-Lys-Gln-Ile-Ala-Cys-Arg-Leu-Tyr-Asn-Thr-Cys (Disulfide bridge: Cys20-Cys26)
Appearance
Powder
Purity
≥97%
Sequence
SIITMTKEAKLPQLWKQIACRLYNTC (Disulfide bridge: Cys20-Cys26)
Storage
Store at -20°C
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