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Pleurain-D4

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Pleurain-D4 is an antimicrobial peptide found in skin secretions, Rana pleuraden, Yunnan pond frog. It has antibacterial activity against gram-negative bacteria Escherichia coli (MIC=50 μg/ml) and gram-positive bacteria Staphylococcus aureus (MIC=12.5 μg/ml), Bacillus subtilis (MIC=50 μg/ml), and has anti-yeast activity against Candida albicans (MIC=25 μg/ml).

Category

Functional Peptides

Catalog number

BAT-011521

Molecular Formula

C111H192N30O28S2

Molecular Weight

2459.06

Specification

IUPAC Name

(4R,7S,10S,13S,16S,19S,22R)-22-((S)-2-((S)-2-((S)-2-((S)-1-(L-phenylalanyl-L-arginyl-L-serylglycyl-L-isoleucyl-L-leucyl-L-lysyl-L-leucyl-L-alanyl-L-seryl-L-lysyl-L-isoleucyl)pyrrolidine-2-carboxamido)-3-hydroxypropanamido)-3-methylbutanamido)-4-methylpentanamido)-7-(2-amino-2-oxoethyl)-10-(4-aminobutyl)-13-isobutyl-16-isopropyl-19-methyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxylic acid

Synonyms

Phe-Arg-Ser-Gly-Ile-Leu-Lys-Leu-Ala-Ser-Lys-Ile-Pro-Ser-Val-Leu-Cys-Ala-Val-Leu-Lys-Asn-Cys (Disulfide bridge: Cys17-Cys23); Pleurain-D4 antimicrobial peptide

Appearance

Powder

Purity

≥96%

Sequence

FRSGILKLASKIPSVLCAVLKNC (Disulfide bridge: Cys17-Cys23)

Storage

Store at -20°C