Pomalidomide-C2-NH2
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Pomalidomide-C2-NH2

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Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Category
Peptide Synthesis Reagents
Catalog number
BAT-006493
CAS number
1957235-66-3
Molecular Formula
C15H16N4O4
Molecular Weight
316.31
Pomalidomide-C2-NH2
Size Price Stock Quantity
25 mg $199 In stock
100 mg $523 In stock
IUPAC Name
4-(2-aminoethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Synonyms
4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Appearance
White to Yellow Powder
Purity
> 98%
Density
1.496±0.06 g/cm3 (Predicted)
Boiling Point
633.6±55.0 °C (Predicted)
Storage
2 - 8 °C, protect from light.
Solubility
10 mM in DMSO
InChI
InChI=1S/C15H16N4O4/c16-6-7-17-9-3-1-2-8-12(9)15(23)19(14(8)22)10-4-5-11(20)18-13(10)21/h1-3,10,17H,4-7,16H2,(H,18,20,21)
InChI Key
WYIGFEKILOYHCT-UHFFFAOYSA-N
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCN
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