Pomalidomide-C4-NH2
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Pomalidomide-C4-NH2

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Pomalidomide-C4-NH2 is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology.

Category
Peptide Synthesis Reagents
Catalog number
BAT-006305
CAS number
1957236-34-8
Molecular Formula
C17H20N4O4
Molecular Weight
344.37
Pomalidomide-C4-NH2
IUPAC Name
4-(4-aminobutylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Synonyms
4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-; Thalidomide-NH-C4-NH2
Related CAS
2093387-50-7 (TFA salt) 2162120-73-0 (hydrochloride)
Appearance
White to Off-white Solid
Purity
≥95%
Density
1.4±0.1 g/cm3
Boiling Point
641.4±55.0°C at 760 mmHg
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
InChI
InChI=1S/C17H20N4O4/c18-8-1-2-9-19-11-5-3-4-10-14(11)17(25)21(16(10)24)12-6-7-13(22)20-15(12)23/h3-5,12,19H,1-2,6-9,18H2,(H,20,22,23)
InChI Key
KMGOFKGAYSFPGS-UHFFFAOYSA-N
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCN
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