(R)-N-Boc-piperidine-2-methanol
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(R)-N-Boc-piperidine-2-methanol

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(R)-N-Boc-piperidine-2-methanol (CAS# 134441-61-5) is a useful research chemical.

Category
Amino Alcohol
Catalog number
BAT-000617
CAS number
134441-61-5
Molecular Formula
C11H21NO3
Molecular Weight
215.29
(R)-N-Boc-piperidine-2-methanol
IUPAC Name
tert-butyl (2R)-2-(hydroxymethyl)piperidine-1-carboxylate
Synonyms
(R)-1-N-Boc-2-Hydroxymethylpiperidine; (R)-N-Boc-piperidine-2-methanol; (R)-tert-butyl 2-(hydroxymethyl)piperidine-1-carboxylate
Appearance
White powder
Purity
≥ 95 % (NMR)
Density
1.059 g/cm3
Boiling Point
308 ℃ at 760 mmHg
Storage
Store at 2-8 ℃
InChI
InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-7-5-4-6-9(12)8-13/h9,13H,4-8H2,1-3H3/t9-/m1/s1
InChI Key
PZTAGFCBNDBBFZ-SECBINFHSA-N
Canonical SMILES
CC(C)(C)OC(=O)N1CCCCC1CO
1. Linking big five personality traits to sexuality and sexual health: A meta-analytic review
Mark S Allen, Emma E Walter Psychol Bull. 2018 Oct;144(10):1081-1110. doi: 10.1037/bul0000157. Epub 2018 Jun 7.
This meta-analytic review addresses whether the major dimensions of trait personality relate to components of human sexuality. A comprehensive literature search identified 137 studies that met inclusion criteria (761 effect sizes; total n = 420,595). Pooled mean effects were computed using inverse-variance weighted random effects meta-analysis. Mean effect sizes from 100 separate meta-analyses provided evidence that personality relates to theoretically predicted components of sexuality and sexual health. Neuroticism was positively related to sexual dissatisfaction (r+ = .18), negative emotions (r+ = .42), and symptoms of sexual dysfunction (r+ = .16). Extraversion was positively related to sexual activity (r+ = .17) and risky sexual behavior (r+ = .18), and negatively related to symptoms of sexual dysfunction (r+ = -.17). Openness was positively related to homosexual orientation (r+ = .16) and liberal attitudes toward sex (r+ = .19). Agreeableness and conscientiousness were negatively related to sexually aggressive behavior (r+ = -.20; r+ = -.14) and sexual infidelity (r+ = -.18; r+ = -.17). Less robust evidence indicated that extraversion related negatively, and neuroticism positively, to child sexual abuse, and that openness related negatively to homophobic attitudes. Random effects metaregression identified age, gender, and study quality as important moderators of pooled mean effects. These findings might be of interest to health care professionals developing health care services that aim to promote sexually healthy societies. (PsycINFO Database Record
2. Relationship between core stability, functional movement, and performance
Tomoko Okada, Kellie C Huxel, Thomas W Nesser J Strength Cond Res. 2011 Jan;25(1):252-61. doi: 10.1519/JSC.0b013e3181b22b3e.
The purpose of this study was to determine the relationship between core stability, functional movement, and performance. Twenty-eight healthy individuals (age = 24.4 ± 3.9 yr, height = 168.8 ± 12.5 cm, mass = 70.2 ± 14.9 kg) performed several tests in 3 categories: core stability (flexion [FLEX], extension [EXT], right and left lateral [LATr/LATl]), functional movement screen (FMS) (deep squat [DS], trunk-stability push-up [PU], right and left hurdle step [HSr/HSl], in-line lunge [ILLr/ILLl], shoulder mobility [SMr/SMl], active straight leg raise [ASLRr/ASLRl], and rotary stability [RSr/RSl]), and performance tests (backward medicine ball throw [BOMB], T-run [TR], and single leg squat [SLS]). Statistical significance was set at p ≤ 0.05. There were significant correlations between SLS and FLEX (r = 0.500), LATr (r = 0.495), and LATl (r = 0.498). The TR correlated significantly with both LATr (r = 0.383) and LATl (r = 0.448). Of the FMS, BOMB was significantly correlated with HSr (r = 0.415), SMr (r = 0.388), PU (r = 0.407), and RSr (r = 0.391). The TR was significantly related with HSr (r = 0.518), ILLl (r = 0.462) and SMr (r = 0.392). The SLS only correlated significantly with SMr (r = 0.446). There were no significant correlations between core stability and FMS. Moderate to weak correlations identified suggest core stability and FMS are not strong predictors of performance. In addition, existent assessments do not satisfactorily confirm the importance of core stability on functional movement. Despite the emphasis fitness professionals have placed on functional movement and core training for increased performance, our results suggest otherwise. Although training for core and functional movement are important to include in a fitness program, especially for injury prevention, they should not be the primary emphasis of any training program.
3. Management of thyroid cancer: United Kingdom National Multidisciplinary Guidelines
A L Mitchell, A Gandhi, D Scott-Coombes, P Perros Practice J Laryngol Otol. 2016 May;130(S2):S150-S160. doi: 10.1017/S0022215116000578.
This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper provides recommendations on the management of thyroid cancer in adults and is based on the 2014 British Thyroid Association guidelines. Recommendations · Ultrasound scanning (USS) of the nodule or goitre is a crucial investigation in guiding the need for fine needle aspiration cytology (FNAC).
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