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Ranatuerin-4

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Ranatuerin-4 is an antimicrobial peptide found in Rana catesbeiana (Lithobates catesbeianus, North American bull frog), and has antibacterial activity against gram-positive bacterium S.aureus (MIC=55 µM). It shows no detectable hemolytic activity towards human erythrocytes.

Category
Functional Peptides
Catalog number
BAT-011441
CAS number
215715-54-1
Molecular Formula
C126H204N30O28S2
Molecular Weight
2651.27
IUPAC Name
(4R,7S,10S,13S,16S,19S,22R)-22-((2S,3S)-2-((2S,3S)-2-((S)-2-((S)-1-(L-phenylalanyl-L-leucyl-L-prolyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-arginyl-L-leucyl-L-alanyl-L-alanyl-L-lysyl-L-valyl-L-phenylalanyl)pyrrolidine-2-carboxamido)-3-hydroxypropanamido)-3-methylpentanamido)-3-methylpentanamido)-7,10-bis(4-aminobutyl)-13-((R)-1-hydroxyethyl)-19-(hydroxymethyl)-16-isopropyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxylic acid
Synonyms
Phe-Leu-Pro-Phe-Ile-Ala-Arg-Leu-Ala-Ala-Lys-Val-Phe-Pro-Ser-Ile-Ile-Cys-Ser-Val-Thr-Lys-Lys-Cys (Disulfide bridge: Cys18-Cys24)
Appearance
Lyophilized Powder
Purity
≥96%
Sequence
FLPFIARLAAKVFPSIICSVTKKC (Disulfide bridge: Cys18-Cys24)
Storage
Store at -20°C
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