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Ranatuerin-6

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Ranatuerin-6 is an antimicrobial peptide found in Rana catesbeiana (Lithobates catesbeianus, North American bull frog), and has antibacterial activity against gram-positive bacterium S.aureus (MIC=100 µM). It shows no detectable hemolytic activity towards human erythrocytes. It can inhibit HIV infection <10% at a concentration that is also toxic to T cells.

Category

Functional Peptides

Catalog number

BAT-011443

Molecular Formula

C67H108N14O16S

Molecular Weight

1397.72

Specification

IUPAC Name

L-phenylalanyl-L-isoleucyl-L-seryl-L-alanyl-L-isoleucyl-L-alanyl-L-seryl-L-methionyl-L-leucylglycyl-L-lysyl-L-phenylalanyl-L-leucine

Synonyms

H-Phe-Ile-Ser-Ala-Ile-Ala-Ser-Met-Leu-Gly-Lys-Phe-Leu-OH

Related CAS

215715-56-3 (reduced)

Appearance

Powder

Purity

≥97%

Density

1.219±0.1 g/cm3

Boiling Point

1661.5±65.0°C at 760 mmHg

Sequence

FISAIASMLGKFL

Storage

Store at -20°C

InChI

InChI=1S/C67H109N15O15S/c1-12-39(7)54(81-58(88)42(10)72-64(94)51(35-83)80-67(97)55(40(8)13-2)82-59(89)45(69)32-43-22-16-14-17-23-43)66(96)73-41(9)57(87)79-52(36-84)65(95)75-47(27-29-98-11)62(92)77-49(31-38(5)6)60(90)71-34-53(85)74-46(26-20-21-28-68)61(91)78-50(33-44-24-18-15-19-25-44)63(93)76-48(56(70)86)30-37(3)4/h14-19,22-25,37-42,45-52,54-55,83-84H,12-13,20-21,26-36,68-69H2,1-11H3,(H2,70,86)(H,71,90)(H,72,94)(H,73,96)(H,74,85)(H,75,95)(H,76,93)(H,77,92)(H,78,91)(H,79,87)(H,80,97)(H,81,88)(H,82,89)/t39-,40-,41-,42-,45-,46-,47-,48-,49-,50-,51-,52-,54-,55-/m0/s1

InChI Key

SXUDAOJRHYLPNH-HCYLHJIASA-N

Canonical SMILES

CCC(C)C(C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(C(C)CC)NC(=O)C(CC2=CC=CC=C2)N