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RETF-4NA

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RETF-4NA is a sensitive substrate for chymase when free or bound to α2M. It is selectively hydrolyzed by chymase but not by cathepsin G.

Category

Peptide Inhibitors

Catalog number

BAT-010838

CAS number

1160928-63-1

Molecular Formula

C32H43N9O10

Molecular Weight

713.75

Size	Price	Stock	Quantity
10 mg	$178	In stock

Specification

IUPAC Name

4-[[2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[3-hydroxy-1-[[1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Synonyms

acetyl-L-Arg-Glu-Thr-Phe-4-nitroanilide

Sequence

Ac-DL-Arg-DL-Glu-DL-xiThr-DL-Phe-pNA

Storage

Store at -20°C

InChI

InChI=1S/C32H43N9O10/c1-18(42)27(40-29(47)24(14-15-26(44)45)38-28(46)23(36-19(2)43)9-6-16-35-32(33)34)31(49)39-25(17-20-7-4-3-5-8-20)30(48)37-21-10-12-22(13-11-21)41(50)51/h3-5,7-8,10-13,18,23-25,27,42H,6,9,14-17H2,1-2H3,(H,36,43)(H,37,48)(H,38,46)(H,39,49)(H,40,47)(H,44,45)(H4,33,34,35)/t18-,23+,24+,25+,27+/m1/s1

InChI Key

MGCWUIJMQAZRNY-SJYYQWPBSA-N

Canonical SMILES

CC(C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C)O