RNAIII-inhibiting peptide TFA
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RNAIII-inhibiting peptide TFA

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RNAIII-inhibiting peptide (TFA), a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases.

Category
Peptide Inhibitors
Catalog number
BAT-009338
CAS number
2703745-76-8
Molecular Formula
C45H56N10O11.C2HF3O2
Molecular Weight
1027.01
RNAIII-inhibiting peptide TFA
IUPAC Name
(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]butanediamide;2,2,2-trifluoroacetic acid
Synonyms
H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2.TFA; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide trifluoroacetic acid; RNAIII-inhibiting peptide trifluoroacetic acid; RNAIII-inhibiting peptide (TFA)
Related CAS
661485-29-6 (free base)
Appearance
White Lyophilized Powder
Purity
>98%
Sequence
YSPWTNF-NH2.TFA
Storage
Store at -20°C
Solubility
Soluble in DMSO
InChI
InChI=1S/C45H56N10O11.C2HF3O2/c1-24(57)38(44(65)52-34(21-37(47)59)41(62)50-32(39(48)60)19-25-8-3-2-4-9-25)54-42(63)33(20-27-22-49-31-11-6-5-10-29(27)31)51-43(64)36-12-7-17-55(36)45(66)35(23-56)53-40(61)30(46)18-26-13-15-28(58)16-14-26;3-2(4,5)1(6)7/h2-6,8-11,13-16,22,24,30,32-36,38,49,56-58H,7,12,17-21,23,46H2,1H3,(H2,47,59)(H2,48,60)(H,50,62)(H,51,64)(H,52,65)(H,53,61)(H,54,63);(H,6,7)/t24-,30+,32+,33+,34+,35+,36+,38+;/m1./s1
InChI Key
UFMWBLWECSYAKK-TUPMYQNZSA-N
Canonical SMILES
CC(C(C(=O)NC(CC(=O)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C4CCCN4C(=O)C(CO)NC(=O)C(CC5=CC=C(C=C5)O)N)O.C(=O)(C(F)(F)F)O
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