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RS09 2TFA

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

RS09 2TFA, a TLR4 agonist, is an adjuvant that promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS09 increases antibody production in the vaccine environment.

Category

Peptide Inhibitors

Catalog number

BAT-016299

Molecular Formula

C35H51F6N9O13

Molecular Weight

919.82

Specification

IUPAC Name

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid;2,2,2-trifluoroacetic acid

Synonyms

H-Ala-Pro-Pro-His-Ala-Leu-Ser-OH.2TFA; L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine trifluoroacetic acid; RS 09 2TFA

Related CAS

1449566-36-2 (free base)

Purity

≥95%

Sequence

APPHALS.2TFA

Storage

Store at -20°C

Solubility

Soluble in DMSO

InChI

InChI=1S/C31H49N9O9.2C2HF3O2/c1-16(2)11-20(27(44)38-22(14-41)31(48)49)36-25(42)18(4)35-26(43)21(12-19-13-33-15-34-19)37-28(45)23-7-5-9-39(23)30(47)24-8-6-10-40(24)29(46)17(3)32;2*3-2(4,5)1(6)7/h13,15-18,20-24,41H,5-12,14,32H2,1-4H3,(H,33,34)(H,35,43)(H,36,42)(H,37,45)(H,38,44)(H,48,49);2*(H,6,7)/t17-,18-,20-,21-,22-,23-,24-;;/m0../s1

InChI Key

MKCNGKQUSQZTFM-AZNUZYABSA-N

Canonical SMILES

CC(C)CC(C(=O)NC(CO)C(=O)O)NC(=O)C(C)NC(=O)C(CC1=CN=CN1)NC(=O)C2CCCN2C(=O)C3CCCN3C(=O)C(C)N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O