(S)-3-[(9-Fluorenylmethoxycarbonyl)amino]-5-phenylpentanoic acid
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(S)-3-[(9-Fluorenylmethoxycarbonyl)amino]-5-phenylpentanoic acid

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Fmoc-(S)-3-amino-5-phenylpentanoic Acid is an intermediate used in the synthesis of chemical modulators of heat shock protein 70 (Hsp70). It is also used to prepare guanidinoglycosides with inventive use of Mitsunobu conditions and diazabicycloundecene.

Category
Fmoc-Amino Acids
Catalog number
BAT-005365
CAS number
219967-74-5
Molecular Formula
C26H25NO4
Molecular Weight
415.49
(S)-3-[(9-Fluorenylmethoxycarbonyl)amino]-5-phenylpentanoic acid
IUPAC Name
(3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-5-phenylpentanoic acid
Synonyms
Fmoc-Hph-(C#CH2)OH; Fmoc-Phe(#CH2,C#CH2)-OH; Fmoc-(S)-3-amino-5-phenylpentanoic acid; Fmoc-b-Nva(5-phenyl)-OH; N-(9-FLUORENYLMETHOXYCARBONYL)-(S)-3-AMINO-5-PHENYLPENTANOIC ACID; (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoic acid; Fmoc-L-β-Nva(5-phenyl)-OH
Appearance
White to off-white powder
Purity
≥ 95%
Density
1.234±0.060 g/cm3
Melting Point
176-177 °C
Boiling Point
657.5±55.0 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C26H25NO4/c28-25(29)16-19(15-14-18-8-2-1-3-9-18)27-26(30)31-17-24-22-12-6-4-10-20(22)21-11-5-7-13-23(21)24/h1-13,19,24H,14-17H2,(H,27,30)(H,28,29)/t19-/m0/s1
InChI Key
FYJRCXFXXJMPFO-IBGZPJMESA-N
Canonical SMILES
C1=CC=C(C=C1)CCC(CC(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
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