Need Assistance?

US & Canada:
+
UK: +

Our Highlights

GMP Grade Efficient workshop for GMP production.
Optimal Prices Buying products on this site guarantees the best price!
Commercial Batches Independent GMP manufacturing suites that handle commercial batches
Prompt Delivery Warehouses in multiple cities to ensure timely delivery
Flexible Quantity Quantities available from milligrams to ton

(Ser(PO3H2)273)-Nek11 (268-283)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

In undisturbed and DNA-damaged cells, depletion of NEK11 prevents proteasome-dependent CDC25A degradation. NEK11 directly phosphorylates CDC25A, and CHK1 (checkpoint kinase 1) is activated directly by phosphorylation of NEK11 at Ser273. NEK11 is an important component of the G2/M checkpoint pathway, and genetic mutations in NEK11 may contribute to cancer development.

Category

Functional Peptides

Catalog number

BAT-014831

CAS number

2243207-06-7

Molecular Formula

C77H135N22O26PS

Molecular Weight

1848.09

Specification

Synonyms

H-Leu-Asn-Lys-Asn-Pro-Ser(PO3H2)-Leu-Arg-Pro-Ser-Ala-Ile-Glu-Ile-Leu-Cys-OH; L-Cysteine, L-leucyl-L-asparaginyl-L-lysyl-L-asparaginyl-L-prolyl-O-phosphono-L-seryl-L-leucyl-L-arginyl-L-prolyl-L-seryl-L-alanyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-leucyl-

Appearance

White Powder

Purity

≥95%

Sequence

LNKNP(PO3H2)SLRPSAIEILC

Storage

Store at -20°C

Solubility

Soluble in Acetic Acid