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SNAP8 acetate

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SNAP8 acetate is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation and preventing the formation of lines and wrinkles.

Category
Functional Peptides
Catalog number
BAT-016144
Molecular Formula
C43H74N16O18S
Molecular Weight
1135.21
SNAP8 acetate
IUPAC Name
(4S)-4-acetamido-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-carboxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;acetic acid
Synonyms
N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-α-asparagine acetate salt; Acetyl octapeptide 1 acetate salt; Acetyl octopeptide 3 acetate salt; Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2.CH3CO2H
Related CAS
868844-74-0 (free base)
Purity
≥95%
Sequence
Ac-EEMQRRAD-NH2.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in DMSO
InChI
InChI=1S/C41H70N16O16S.C2H4O2/c1-19(33(67)57-27(32(43)66)18-31(64)65)50-34(68)21(6-4-15-48-40(44)45)52-35(69)22(7-5-16-49-41(46)47)53-37(71)24(8-11-28(42)59)54-39(73)26(14-17-74-3)56-38(72)25(10-13-30(62)63)55-36(70)23(51-20(2)58)9-12-29(60)61;1-2(3)4/h19,21-27H,4-18H2,1-3H3,(H2,42,59)(H2,43,66)(H,50,68)(H,51,58)(H,52,69)(H,53,71)(H,54,73)(H,55,70)(H,56,72)(H,57,67)(H,60,61)(H,62,63)(H,64,65)(H4,44,45,48)(H4,46,47,49);1H3,(H,3,4)/t19-,21-,22-,23-,24-,25-,26-,27-;/m0./s1
InChI Key
XAGQYGDTFYHPEF-OQZVEECESA-N
Canonical SMILES
CC(C(=O)NC(CC(=O)O)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C.CC(=O)O
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