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SV40 T-Ag-derived NLS peptide

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

SV40 T-Ag-derived NLS peptide, derived from the Large T antigen residues 47 to 56, is the nuclear localization signal DNA tagged to this peptide, which is effectively translocated into the nucleus.

Category

Functional Peptides

Catalog number

BAT-009363

CAS number

105425-98-7

Molecular Formula

C66H111N19O18S

Molecular Weight

1490.77

Specification

IUPAC Name

(4S)-4-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-pyrrolidine-2-carbonyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]-5-[[(2S)-3-carboxy-1-[(2S)-2-[[(2S)-1-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

Synonyms

H-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Asp-Pro-Tyr-Cys-OH; SV40 T-Ag-derived Nuclear Localization Signal (NLS) Peptide; NLS Fragment 1; T-NLS peptide; L-Cysteine, L-prolyl-L-lysyl-L-lysyl-L-lysyl-L-arginyl-L-lysyl-L-valyl-L-α-glutamyl-L-α-aspartyl-L-prolyl-L-tyrosyl-

Appearance

White or Off-white Lyophilized Powder

Purity

≥95%

Density

1.47±0.1 g/cm3 (Predicted)

Sequence

PKKKRKVEDPYC

Storage

Store at -20°C

Solubility

Soluble in Water

InChI

InChI=1S/C66H111N19O18S/c1-37(2)53(63(100)80-46(25-26-51(87)88)59(96)82-48(35-52(89)90)64(101)85-33-13-20-50(85)62(99)81-47(34-38-21-23-39(86)24-22-38)61(98)83-49(36-104)65(102)103)84-60(97)44(17-6-10-30-70)78-58(95)45(19-12-32-74-66(71)72)79-57(94)43(16-5-9-29-69)77-56(93)42(15-4-8-28-68)76-55(92)41(14-3-7-27-67)75-54(91)40-18-11-31-73-40/h21-24,37,40-50,53,73,86,104H,3-20,25-36,67-70H2,1-2H3,(H,75,91)(H,76,92)(H,77,93)(H,78,95)(H,79,94)(H,80,100)(H,81,99)(H,82,96)(H,83,98)(H,84,97)(H,87,88)(H,89,90)(H,102,103)(H4,71,72,74)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1

InChI Key

FXFSZTNEZJDYRD-SSLVDESGSA-N

Canonical SMILES

CC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)N1CCCC1C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CS)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C3CCCN3