t-Boc-N-amido-PEG2-amine
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t-Boc-N-amido-PEG2-amine

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Boc-NH-PEG2-C2-NH2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2-C2-NH2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2-C2-NH2 is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.

Category
Peptide Synthesis Reagents
Catalog number
BAT-006486
CAS number
153086-78-3
Molecular Formula
C11H24N2O4
Molecular Weight
248.32
t-Boc-N-amido-PEG2-amine
IUPAC Name
tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Synonyms
NHBoc-PEG2-amine; Boc-NH-PEG2-C2-NH2; BocNH-PEG2-CH2CH2NH2; N-(tert-Butoxycarbonyl)-3,6-dioxa-1,8-octanediaminetert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; Boc-1-amino-3,6-dioxa-8-octanediamine; N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine; N-Boc-2,2'-(ethylenedioxy)diethylamine; N-Boc-3,6-dioxaoctane-1,8-diamine; Boc-N-amido-PEG2-Amine; N-Boc-3,6-dioxa-1,8-octanediamine; 1-(t-Butyloxycarbonyl-amino)-3,6-dioxa-8-octaneamine
Related CAS
890091-42-6 (polymer) 198227-38-2 (polymer)
Appearance
Light Yellow Oily Liquid
Purity
≥95%
Density
1.046 g/mL at 20°C
Boiling Point
365.2±27.0°C (Predicted)
Storage
Store at 2-8°C under inert gas (nitrogen or Argon)
Solubility
Soluble in DMSO (10 mm)
InChI
InChI=1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)
InChI Key
OCUICOFGFQENAS-UHFFFAOYSA-N
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCN
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