TAT 48-57 - CAS 253141-50-3

It is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residues 48-57.

Category
Functional Peptides
Catalog number
BAT-009369
CAS number
253141-50-3
Molecular Formula
C55H109N31O12
Molecular Weight
1396.65
IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Synonyms
H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine; Tat protein (48-57); TAT (48-57)
Appearance
White Lyophilized Powder
Purity
≥95%
Density
1.6±0.1 g/cm3
Sequence
GRKKRRQRRR
Storage
Store at -20°C
Solubility
Soluble in water for a solution up to 2 mg/ml, otherwise acetonitrile is recommended. Avoid repeated freezing and thawing.
InChI
InChI=1S/C55H109N31O12/c56-21-3-1-11-31(79-41(89)30(78-40(88)29-58)13-5-23-72-50(60)61)42(90)80-32(12-2-4-22-57)43(91)81-33(14-6-24-73-51(62)63)44(92)82-35(16-8-26-75-53(66)67)46(94)85-37(19-20-39(59)87)48(96)84-34(15-7-25-74-52(64)65)45(93)83-36(17-9-27-76-54(68)69)47(95)86-38(49(97)98)18-10-28-77-55(70)71/h30-38H,1-29,56-58H2,(H2,59,87)(H,78,88)(H,79,89)(H,80,90)(H,81,91)(H,82,92)(H,83,93)(H,84,96)(H,85,94)(H,86,95)(H,97,98)(H4,60,61,72)(H4,62,63,73)(H4,64,65,74)(H4,66,67,75)(H4,68,69,76)(H4,70,71,77)/t30-,31-,32-,33-,34-,35-,36-,37-,38-/m0/s1
InChI Key
AJFGTSYBZVRLJD-IWLMWFOOSA-N
Canonical SMILES
C(CCN)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)CN
Bio Calculators
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It is commonly abbreviated as: C1V1 = C2V2

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