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Thalidomide-O-COOH

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Thalidomide-O-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.

Category

Peptide Synthesis Reagents

Catalog number

BAT-006489

CAS number

1061605-21-7

Molecular Formula

C15H12N2O7

Molecular Weight

332.26

Specification

IUPAC Name

2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetic acid

Synonyms

E3 ligase Ligand 3; Thalidomide-Acid; Thalidomide-carboxylic acid; 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid; 2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid

Appearance

Beige Powder

Purity

≥ 98%

Density

1.606±0.06 g/cm3 (Predicted)

Boiling Point

660.5±55.0 °C (Predicted)

Storage

-20 °C

InChI

InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)