Tosyl phenylalanyl chloromethyl ketone (BAT-008109)

Tosyl phenylalanyl chloromethyl ketone (TPCK) is an irreversible inhibitor of chymotrypsin-like proteases. It also inhibits some cysteine proteases such as caspase, papain, bromelain or ficin.

Category
Other Unnatural Amino Acids
Catalog number
BAT-008109
CAS number
402-71-1
Molecular Formula
C17H18ClNO3S
Molecular Weight
351.8
Tosyl phenylalanyl chloromethyl ketone
IUPAC Name
N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide
Synonyms
Nα-Tosyl-L-Phenylalanine Chloromethyl Ketone; TPCK; Tos-Phe-CH2Cl
Appearance
White powder
Purity
≥98%
Density
1.277 g/cm3
Melting Point
106-110 °C
Boiling Point
509.9ºC at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1
InChI Key
MQUQNUAYKLCRME-INIZCTEOSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)CCl
Bio Calculators
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
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