(Val2)-Amyloid β-Protein (1-42)
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(Val2)-Amyloid β-Protein (1-42)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

This is a mutation very close to the APP (A673V) β-secretase cleavage site. In contrast to the protective Icelandic mutation A2T, the recessive A2V mutation may increase the risk of Alzheimer's disease. APP A673V is associated with the early onset of AD dementia in homozygous individuals and has a protective effect in the heterozygous states.

Category
Functional Peptides
Catalog number
BAT-014824
Molecular Formula
C205H315N55O60S
Molecular Weight
4542.16
Synonyms
H-Asp-Val-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Appearance
White Powder
Purity
≥95%
Sequence
DVEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Storage
Store at -20°C
Solubility
Soluble in DMF
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