Z-Ala-Pro-Phe-chloromethylketone
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Z-Ala-Pro-Phe-chloromethylketone

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Z-Ala-Pro-Phe-chloromethylketone is an inhibitor of the Ca2+- regulated nuclear scaffold proteinase (CRNSP).

Category
Peptide Inhibitors
Catalog number
BAT-014960
CAS number
217658-18-9
Molecular Formula
C26H30ClN3O5
Molecular Weight
499.99
IUPAC Name
benzyl N-[(2S)-1-[(2S)-2-[[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
Synonyms
Z-APF-CMK; N-benzyloxycarbonyl-Ala-Pro-Phe-chloromethyl ketone
Appearance
White Powder
Purity
>98%
Sequence
Cbz-Ala-Pro-Phe-CH2Cl
InChI
InChI=1S/C26H30ClN3O5/c1-18(28-26(34)35-17-20-11-6-3-7-12-20)25(33)30-14-8-13-22(30)24(32)29-21(23(31)16-27)15-19-9-4-2-5-10-19/h2-7,9-12,18,21-22H,8,13-17H2,1H3,(H,28,34)(H,29,32)/t18-,21-,22-/m0/s1
InChI Key
CSTMIHZYNKMFSL-NYVOZVTQSA-N
Canonical SMILES
CC(C(=O)N1CCCC1C(=O)NC(CC2=CC=CC=C2)C(=O)CCl)NC(=O)OCC3=CC=CC=C3
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