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Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Z-GGR-AMC has been used as a substrate in a direct fluorometric assay of urokinase and tissue-type plasminogen activator as well as for assaying trypsin and thrombin.

Category

Others

Catalog number

BAT-015517

CAS number

102601-58-1

Molecular Formula

C28H34ClN7O7

Molecular Weight

616.07

Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride

Specification

IUPAC Name

benzyl N-[2-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamate;hydrochloride

Synonyms

Z-Gly-Gly-Arg-Amc hydrochloride; (S)-benzyl 2-(2-(5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-2-oxoethylamino)-2-oxoethylcarbamate hydrochloride

Appearance

White to Pale Yellow Solid

Purity

95%

Boiling Point

1000.9ºC at 760 mmHg

Sequence

Cbz-Gly-Gly-Arg-AMC

Storage

Store at -20°C

Solubility

Soluble in Methanol (Slightly), Water (Slightly)

InChI

InChI=1S/C28H33N7O7.ClH/c1-17-12-25(38)42-22-13-19(9-10-20(17)22)34-26(39)21(8-5-11-31-27(29)30)35-24(37)15-32-23(36)14-33-28(40)41-16-18-6-3-2-4-7-18;/h2-4,6-7,9-10,12-13,21H,5,8,11,14-16H2,1H3,(H,32,36)(H,33,40)(H,34,39)(H,35,37)(H4,29,30,31);1H

InChI Key

AYMJBLVMUDFWTM-UHFFFAOYSA-N

Canonical SMILES

CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)CNC(=O)OCC3=CC=CC=C3.Cl