CAS 5672-83-3 Z-L-glutamic acid a-methyl ester

Z-L-glutamic acid a-methyl ester (BAT-003338)

* For research use only

Category

CBZ-Amino Acids

Catalog number

BAT-003338

CAS number

5672-83-3

Molecular Formula

C14H17NO6

Molecular Weight

295.29

Specification
Reference Reading

Synonyms
Synonyms	Z-L-Glu-Ome; 1-Methyl N-Carbobenzoxy-L-Glutamate; N-Cbz-L-Glutamic Acid 1-Methyl Ester
Appearance
Appearance	White powder
Purity
Purity	≥ 98% (HPLC)
Density
Density	1.272 g/cm3
Melting Point
Melting Point	64-72 ºC
Boiling Point
Boiling Point	510.6°C
Storage
Storage	Store at 2-8 °C
InChI
InChI	InChI=1S/C14H17NO6/c1-20-13(18)11(7-8-12(16)17)15-14(19)21-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,15,19)(H,16,17)/t11-/m0/s1
InChI Key
InChI Key	BGMCTGARFXPQML-NSHDSACASA-N
Canonical SMILES
Canonical SMILES	COC(=O)C(CCC(=O)O)NC(=O)OCC1=CC=CC=C1

1.Characterization of the S'-subsite specificity of V8 proteinase via acyl transfer to added nucleophiles.

Schuster M1, Aaviksaar A, Schellenberger V, Jakubke HD. Biochim Biophys Acta. 1990 Dec 6;1036(3):245-7.

The S'-subsite specificity of endoproteinase Glu-C (V8 proteinase) was studied by acyl transfer reactions using Z-Glu-OMe as acyl donor and a series of amino acid- and peptide-derived nucleophiles. The partition constant, which characterizes specificity, was determined by a method based on the integrated rate equation. V8 proteinase prefers amino acid residues with hydrophobic side chains in the P'1 position. Di- and tripeptide amides are more efficient nucleophilic amino components than amino acid amides.

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