Z-L-glutamic acid α-tert-butyl ester dicyclohexylammonium salt
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Z-L-glutamic acid α-tert-butyl ester dicyclohexylammonium salt

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Category
CBZ-Amino Acids
Catalog number
BAT-003342
CAS number
34897-61-5
Molecular Formula
C17H23NO6·C12H23N
Molecular Weight
518.70
Z-L-glutamic acid α-tert-butyl ester dicyclohexylammonium salt
IUPAC Name
N-cyclohexylcyclohexanamine;(4S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-4-(phenylmethoxycarbonylamino)pentanoic acid
Synonyms
Z-L-Glu-OtBu DCHA; Dicyclohexylamine (S)-4-(((Benzyloxy)Carbonyl)Amino)-5-(Tert-Butoxy)-5-Oxopentanoate
Appearance
White powder
Purity
95%
Melting Point
147-152 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C17H23NO6.C12H23N/c1-17(2,3)24-15(21)13(9-10-14(19)20)18-16(22)23-11-12-7-5-4-6-8-12;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20);11-13H,1-10H2/t13-;/m0./s1
InChI Key
POQMGEMMYVJQOK-ZOWNYOTGSA-N
Canonical SMILES
CC(C)(C)OC(=O)C(CCC(=O)O)NC(=O)OCC1=CC=CC=C1.C1CCC(CC1)NC2CCCCC2

Z-L-glutamic acid α-tert-butyl ester dicyclohexylammonium salt, a versatile chemical compound, is utilized across various research and pharmaceutical domains.

Peptide Synthesis: Serving as a cornerstone in peptide synthesis, Z-L-glutamic acid α-tert-butyl ester dicyclohexylammonium salt functions as a crucial protected amino acid derivative. By facilitating the incorporation of glutamic acid into peptides while preserving its side chain functionality throughout synthetic processes, this compound ensures the precise assembly of peptides with unwavering fidelity, maintaining the intended sequence integrity at every stage of the synthesis journey.

Pharmaceutical Research: Embedded in the realm of drug development, this compound acts as a pivotal intermediate in the synthesis of biologically active molecules. Its selective protection of functional groups plays a vital role in complex multi-step synthetic pathways, streamlining the creation of sophisticated organic frameworks. Researchers leverage its capabilities to craft novel pharmaceuticals targeting specific receptors or enzymes involved in disease pathways.

Chemical Biology: Within the domain of chemical biology, Z-L-glutamic acid α-tert-butyl ester dicyclohexylammonium salt emerges as a key protagonist in unraveling the intricacies of protein structure and function. By integrating this compound into peptide models, scientists delve into the impact of glutamic acid residues on protein stability and interactions. This molecular insight propels the design of molecules for therapeutic purposes, drives protein engineering initiatives, and deepens comprehension of protein-protein interactions at a minutiae level, expanding the horizons of scientific understanding.

Material Science: Spearheading innovation in material science, this compound is leveraged to engineer novel polymers and materials with customized characteristics. Its integration into polymer chains brings about transformative modifications to mechanical properties, solubility, and degradation rates, setting the stage for advanced materials tailored for diverse biomedical applications. From optimizing drug delivery systems to creating biodegradable implants, the versatility of this compound fuels the development of cutting-edge materials with profound implications in the biomedical field.

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