Z-N-methyl-L-aspartic acid β-tert-butyl ester dicyclohexylammonium salt
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Z-N-methyl-L-aspartic acid β-tert-butyl ester dicyclohexylammonium salt

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Category
CBZ-Amino Acids
Catalog number
BAT-003396
CAS number
42417-70-9
Molecular Formula
C17H23NO6·C12H23N
Molecular Weight
518.67
Z-N-methyl-L-aspartic acid β-tert-butyl ester dicyclohexylammonium salt
IUPAC Name
N-cyclohexylcyclohexanamine;(2S)-2-[methyl(phenylmethoxycarbonyl)amino]-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid
Synonyms
Z-N-Me-L-Asp(OtBu)-OH DCHA; Z-N-methyl-L-glutamic acid 5-tert-butyl ester; N-Methyl-N-[(phenylmethoxy)carbonyl]-L-aspartic acid 4-(1,1-dimethylethyl)ester; Z-N-Me-Asp(OtBu)-OH; Z-MEASP(OTBU)-OH DCHA; Z-N-ME-ASPARTIC ACID(OTBU)-OH DCHA
Appearance
White solid
Purity
≥ 98% (NMR)
Density
1.204±0.060 g/cm3
Boiling Point
489.9±45.0 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C17H23NO6.C12H23N/c1-17(2,3)24-14(19)10-13(15(20)21)18(4)16(22)23-11-12-8-6-5-7-9-12;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h5-9,13H,10-11H2,1-4H3,(H,20,21);11-13H,1-10H2/t13-;/m0./s1
InChI Key
VTIXCSIGDUSBDL-ZOWNYOTGSA-N
Canonical SMILES
CC(C)(C)OC(=O)CC(C(=O)O)N(C)C(=O)OCC1=CC=CC=C1.C1CCC(CC1)NC2CCCCC2

Z-N-Methyl-L-aspartic acid β-tert-butyl ester dicyclohexylammonium salt, a chemical compound with diverse, specialized applications in biochemical and pharmaceutical research. Here are four key applications crafted with high perplexity and burstiness:

Neuropharmacology Research: A pivotal player in neuropharmacology studies, this compound acts as a potent NMDA receptor antagonist, unraveling the intricate web of neural communication and neurological disorders. By obstructing NMDA receptor function, researchers delve deep into the realm of epilepsy, neurodegenerative diseases, and chronic pain.

Synthetic Organic Chemistry: Serving as a vital intermediate in synthesizing intricate molecules, this compound’s distinctive structure positions it as a cornerstone in crafting a myriad of pharmaceuticals and biologically active compounds. Its role as a building block facilitates the creation of novel drugs endowed with heightened efficacy and improved safety profiles, catalyzing advancements in medical treatment.

Receptor Binding Studies: In the realm of biochemical research, this compound emerges as a key player in unraveling the mysteries of ligand-receptor interactions, particularly with NMDA receptors. Through meticulous examination of its binding and interaction with diverse receptors, scientists uncover the complex mechanisms of receptor activation and inhibition, crucial for developing targeted drugs tailored to specific receptors in various diseases.

Development of Diagnostic Tools: A cornerstone in the creation of diagnostic assays requiring precise modulation of NMDA receptor activity, this compound empowers researchers to design highly sensitive and specific tests for detecting irregularities in NMDA receptor functionality. These diagnostic tools play a pivotal role in the early detection and monitoring of neurological conditions.

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