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Z-Val-Ala-OH

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Z-Val-Ala-OH is a useful reagent in the preparation and biological evaluation of peptide amide conjugates of nucleosides as prodrugs that are converted to parent drugs by action of DPPIV/CD26. Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme.

Category
Functional Peptides
Catalog number
BAT-006600
CAS number
24787-89-1
Molecular Formula
C16H22N2O5
Molecular Weight
322.36
Z-Val-Ala-OH
IUPAC Name
(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoic acid
Synonyms
Z-L-valyl-L-alanine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-3-Methylbutanamido)Propanoic Acid; Z Val Ala OH
Appearance
White powder
Purity
≥ 98% (HPLC)
Density
1.13g/cm3
Melting Point
165 °C
Boiling Point
513.5°C at 760 mmHg
Storage
Store at 2-8°C
InChI
InChI=1S/C16H22N2O5/c1-10(2)13(14(19)17-11(3)15(20)21)18-16(22)23-9-12-7-5-4-6-8-12/h4-8,10-11,13H,9H2,1-3H3,(H,17,19)(H,18,22)(H,20,21)/t11-,13-/m0/s1
InChI Key
KDQLNJPBTLIYNW-AAEUAGOBSA-N
Canonical SMILES
CC(C)C(C(=O)NC(C)C(=O)O)NC(=O)OCC1=CC=CC=C1
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