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Z-Val-Asp-Val-Ala-Asp-AFC

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Z-VDVAD-AFC is a fluorogenic substrate for caspase-2 (ICH-1).

Category

Others

Catalog number

BAT-015057

CAS number

219138-08-6

Molecular Formula

C39H45F3N6O13

Molecular Weight

862.81

Specification

IUPAC Name

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid

Synonyms

N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine; L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; Z-VDVAD-AFC

Appearance

White Powder

Purity

≥95%

Density

1.399±0.06 g/cm3

Sequence

Cbz-Val-Asp-Val-Ala-Asp-AFC

Storage

Store at -20°C

Solubility

Soluble in Acetic acid, Chloroform, Dimethylformamide, Methanol

InChI

InChI=1S/C39H45F3N6O13/c1-18(2)31(47-35(56)26(16-29(51)52)46-37(58)32(19(3)4)48-38(59)60-17-21-9-7-6-8-10-21)36(57)43-20(5)33(54)45-25(15-28(49)50)34(55)44-22-11-12-23-24(39(40,41)42)14-30(53)61-27(23)13-22/h6-14,18-20,25-26,31-32H,15-17H2,1-5H3,(H,43,57)(H,44,55)(H,45,54)(H,46,58)(H,47,56)(H,48,59)(H,49,50)(H,51,52)/t20-,25-,26-,31-,32-/m0/s1

InChI Key

FYZXTAPKQMDZKT-UXAYAQJLSA-N

Canonical SMILES

CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C(CC(=O)O)NC(=O)C(C(C)C)NC(=O)OCC3=CC=CC=C3