PNA for OLED ApplicationTM (PNA OLEDTM)
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PNA for OLED ApplicationTM (PNA OLEDTM)

Introduction of PNAs

Peptide nucleic acids (PNAs) are synthetic mimics of DNA in which the deoxyribose phosphate backbone is replaced by a pseudopeptide polymer to which the nucleobase is attached. PNAs are capable of hybridizing with complementary DNAs or RNAs with high affinity and specificity. It is due to their unique physico-chemical properties that PNAs have shown strong potential in recent years for molecular biology procedures and diagnostic assays.

  • Widespread Application of PNA
  • Anti-gene and antisense therapeutics agents
  • Anticancer, antiviral, antibacterial and antiparasitic agents
  • Molecular tools and probes for biosensors
  • Detection of DNA sequences
  • Nanotechnology

Introduction of OLEDs

Organic light-emitting diodes (OLEDs) have gained significant attention due to their thinner and smaller size, lighter weight, and cost-effective manufacturing processes. Their application in flat panel displays has shown to be energy efficient and environmentally friendly. OLED technology has progressed significantly over the past decade. However, there is still much room for improvement in terms of efficiency and lifetime of OLED. In particular, the quest for low-cost, high-efficiency and stable blue light-emitting compounds has been the focus of research.

The basic OLED device architecture.Fig 1. The basic OLED device architecture. (Jadoun, S.; Riaz, U. 2020)


Watson-Crick-specific base pairing in PNA domains is known to be excellent self-assembling systems. Stability, biocompatibility, Van der Waals interactions, and water solubility of PNAs make them ideal for biosensing, catalysis, and many other nanotechnology applications. At BOC Sciences, our experts have applied a series of self-assembled PNAs for OLED Application. Our unique PNA OLEDTM platform is well-established to develop electroluminescent/photoluminescent materials based on the unique nanostructures of PNA derivatives to manufacture OLEDs.

  • PNA-based Nanostructures Production

Three guanine (G)-containing PNA dimers, namely CG, GC, and GG that exhibit extensive excitation-dependent fluorescence in the visible region are carefully designed and manufactured:

  • The co-assembly of two paired di-PNA building blocks such as GG and CC can form the well-ordered supramolecular structures that can be regulated and monitored by using microfluidic systems, and these structures can be used for a variety of materials science and nanotechnology applications
  • Self-assembly of PNA N-capped G-monomer N-(N-Fmoc-2-aminoethyl)-N-[(N-6-Bhoc-9-guanyl)acetyl]-glycine is able to yield supramolecular structures with nanospheres, which have unique optical and "structural color" properties, forming photonic crystals that can be used for optoelectronic applications
  • In the absence of any cations such as Na+ and K+, the conjugation of Fmoc-G-aeg-OH with 6-aminohexanoic acid hydrocarbons is able to produce tetrameric supramolecular assembled structures. Comprehensive experimental and theoretical mechanical studies have revealed that such tetrameric supramolecular structures have higher mechanical stiffness as well as significant mechanical stability compared to natural nucleic acid-derived structures
  • Based on quadruplex-inspired peptide nucleic acid based self-assembled tetramer, hydrocarbon conjugated PNAs can also be combined with ruthenium complexes, which can be used as light harvesting catalysts in artificial photosynthesis systems

Applications of OLED.Fig 2. Applications of OLED. (Jadoun, S.; Riaz, U. 2020)

  • Our Achievements
  • Synthesis and assembly of nanostructures
  • Study of physical properties of light luminescent entities
  • Preparation of new building blocks allowing for full spectrum realization of organic light emitting technology
  • Promising Performance Characteristics of PNA OLEDs
  • High emission efficiency
  • Tunable color
  • Better charge-transport and film-forming properties
  • Ease of synthesis
  • Oxidative stability
  • Eco-friendliness,
  • Full spectral support (including the blue color)
  • High quantum yields
  • Application of PNA OLEDs

Given the great potential of light-emitting self-assembled PNAs in photonic crystals and artificial photosynthesis, PNAs can be used as an emitting layer in OLEDs with full-color displays in a variety of dlectroluminescence devices such as TV screens, computer displays, and portable electronics such as cell phones.

Our Focus in the Future

BOC Sciences is currently concentrating on patterning and optimizing the solid surface deposition of this nanostructure. Moreover, our team of experts will perform a proof of concept for this novel technology, for which a working prototype is being designed and developed.


  1. Self-assembled peptide nucleic acids, O. Berger, L. Adler-Abramovich, E. Gazit - US Patent 9,741,948, 2017.
  2. Self-assembled structures composed of monomers of peptide nucleic acid and tunable photonic crystals made therefrom, O. Berger, L. Adler-Abramovich, E. Gazit - US Patent 511,124,543, 2021.
  3. Jadoun, S.; Riaz, U. Conjugated Polymer Light-Emitting Diodes. Polymers for Light-Emitting Devices and Displays. 2020, 4: 77-98.
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