N-α-Formyl-L-cysteine
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N-α-Formyl-L-cysteine

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Category
L-Amino Acids
Catalog number
BAT-002144
CAS number
19538-78-4
Molecular Formula
C4H7NO3S·HCl
Molecular Weight
149.17
IUPAC Name
(2R)-2-formamido-3-sulfanylpropanoic acid
Synonyms
For-Cys-OH
InChI
InChI=1S/C4H7NO3S/c6-2-5-3(1-9)4(7)8/h2-3,9H,1H2,(H,5,6)(H,7,8)/t3-/m0/s1
InChI Key
JTGVRUVUKGUTRL-VKHMYHEASA-N
Canonical SMILES
C(C(C(=O)O)NC=O)S

N-α-Formyl-L-cysteine, a modified amino acid with diverse applications in bioscience research, offers a range of possibilities.

Protein Engineering: Delving into the realm of protein engineering, scientists harness the power of N-α-Formyl-L-cysteine to introduce formyl groups into proteins, enabling precise site-specific labeling and conjugation. This opens doors to studying protein interactions and dynamics with unparalleled specificity. The selective modification of proteins not only aids in understanding biological processes, but also fuels the development of groundbreaking biotherapeutics and diagnostic tools, shaping the future of biotechnological advancement.

Enzyme Catalysis Studies: In the intricate world of enzyme catalysis, N-α-Formyl-L-cysteine plays a critical role in deciphering the functions of formylated amino acids in enzyme activity. By integrating this compound into enzyme structures, scientists unravel the impact of formylation on enzyme kinetics and substrate binding, shedding light on the nuances of enzymatic reactions. These insights are instrumental in designing enzymes with enhanced or modified activities, paving the way for novel industrial applications and biotechnological innovations.

Chemical Biology: Venturing into the realm of chemical biology, N-α-Formyl-L-cysteine emerges as a versatile building block for synthesizing peptidomimetics and other bioactive molecules. Its unique reactivity serves as a catalyst for creating compounds that can modulate intricate biological processes, potentially serving as promising drug candidates. Researchers leverage this modified amino acid to explore uncharted territories in therapeutics and molecular probes, pushing the boundaries of biomedical research and pharmaceutical development.

Redox Biology: Delving into the enigmatic domain of redox biology, N-α-Formyl-L-cysteine takes center stage, particularly in the context of formylation as a post-translational modification. Scientists delve into the exploration of oxidative stress responses and redox signaling pathways within cellular frameworks, unraveling the intricacies of cellular homeostasis. These studies not only deepen our understanding of cellular dynamics but also pave the way for devising strategies to combat oxidative damage, offering insights into potential therapeutic interventions and preventive measures.

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