Fmoc-N-Et-D-Ala-OH
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Fmoc-N-Et-D-Ala-OH

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Category
Fmoc-Amino Acids
Catalog number
BAT-009017
CAS number
1283761-38-5
Molecular Formula
C20H21NO4
Molecular Weight
339.4
IUPAC Name
(2R)-2-[ethyl(9H-fluoren-9-ylmethoxycarbonyl)amino]propanoic acid
Synonyms
Fmoc-D-N(Et)Ala-OH; N-Fmoc-N-ethyl-D-alanine; N-Ethyl-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-D-alanine; Fmoc N Et D Ala OH
Density
1.2±0.1 g/cm3
Boiling Point
523.9±29.0°C at 760 mmHg
InChI
InChI=1S/C20H21NO4/c1-3-21(13(2)19(22)23)20(24)25-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18H,3,12H2,1-2H3,(H,22,23)/t13-/m1/s1
InChI Key
FIVAYWIQBITLAU-CYBMUJFWSA-N
Canonical SMILES
CCN(C(C)C(=O)O)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Fmoc-N-Et-D-Ala-OH, an amino acid derivative commonly utilized in peptide synthesis and research, serves as a cornerstone in various applications. Here are the key applications of Fmoc-N-Et-D-Ala-OH, presented with high perplexity and burstiness:

Peptide Synthesis: Integral to the synthesis of peptides, Fmoc-N-Et-D-Ala-OH imparts specificity and stability to the final product. As a component of the Fmoc group, it streamlines the stepwise construction of peptides, minimizing unwanted side reactions. This compound is indispensable for generating high-purity peptides essential for biochemical and pharmaceutical investigations.

Drug Development: Within the realm of pharmaceuticals, Fmoc-N-Et-D-Ala-OH plays a pivotal role in crafting peptidomimetic drugs. These compounds mimic peptide structures and effectively interact with key biological targets like enzymes and receptors. Leveraging Fmoc-N-Et-D-Ala-OH enables the design of stable and biologically active drug candidates, paving the way for innovative therapeutic solutions.

Structural Studies: Scientists leverage Fmoc-N-Et-D-Ala-OH in structural investigations to probe the 3D conformation of peptides and proteins. This compound aids in constructing specific dipeptide sequences, crucial for unraveling protein folding patterns and intricate interactions. Understanding these structural nuances is paramount for advancing drug discovery and refining protein-based therapeutics.

Bioconjugation: In bioconjugation techniques, Fmoc-N-Et-D-Ala-OH plays a pivotal role in linking peptides to various biomolecules, such as antibodies or nucleic acids. This conjugation process is instrumental in developing targeted drug delivery systems and cutting-edge diagnostic tools. By incorporating Fmoc-N-Et-D-Ala-OH, researchers can engineer bio-functionalized molecules with enhanced specificity and efficacy, driving forward the frontier of biological applications.

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