Fmoc-Sar-Sar-OH
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Fmoc-Sar-Sar-OH

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Fmoc-Sar-Sar-OH is a peptide building block used in solid-phase peptide synthesis. It features an Fmoc (Fluorenylmethyloxycarbonyl) protective group on the N-terminus, which shields the amino group during peptide assembly. The core structure includes two Sar (Sarcosine) residues, a small, non-polar amino acid with a methyl group replacing one hydrogen, contributing to the peptide's flexibility and hydrophobic interactions. The -OH at the C-terminus indicates a free carboxyl group, allowing for further coupling with other amino acids. This compound is utilized to introduce specific dipeptide sequences into larger peptides, influencing their structure and function.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016530
CAS number
2313534-20-0
Molecular Formula
C21H22N2O5
Molecular Weight
382.42
Fmoc-Sar-Sar-OH
IUPAC Name
2-[[2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]acetyl]-methylamino]acetic acid
Synonyms
Fmoc-Sar-Sar; N-(Fluorenylmethoxycarbonyl)-sarcosyl-sarcosine; N-(N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methylglycyl)-N-methylglycine; 2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-N-methylacetamido)acetic acid; N-Fmoc-sarcosyl-sarcosine
Appearance
White to off-white powder
Purity
≥95% by HPLC
Density
1.297±0.06 g/cm3
Boiling Point
600.8±48.0 °C at 760 mmHg
Sequence
Fmoc-Sar-Sar
Storage
Store at RT
InChI
InChI=1S/C21H22N2O5/c1-22(12-20(25)26)19(24)11-23(2)21(27)28-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,18H,11-13H2,1-2H3,(H,25,26)
InChI Key
MBBCNFQALQXGTA-UHFFFAOYSA-N
Canonical SMILES
CN(CC(=O)O)C(=O)CN(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
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