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H-Ser(OtBu)-Ser(OtBu)-Gly-OMe is a protected tripeptide used in peptide synthesis. The H indicates a free N-terminus on the serine (Ser) residue, allowing for further coupling or reactions. The hydroxyl groups on both serine residues are protected by OtBu (tert-butyl) groups, which prevent these groups from reacting until deprotection is carried out. Gly (Glycine), the final amino acid in the sequence, is followed by an OMe (methyl ester) group at the C-terminus, which indicates that the carboxyl group of glycine is esterified. This esterification can help in controlling reactivity or facilitating further modifications. This compound is used to introduce serine and glycine into peptides with specific protections to ensure controlled and efficient peptide synthesis.
