Need Assistance?

US & Canada:
+
UK: +

Our Highlights

GMP Grade Efficient workshop for GMP production.
Optimal Prices Buying products on this site guarantees the best price!
Commercial Batches Independent GMP manufacturing suites that handle commercial batches
Prompt Delivery Warehouses in multiple cities to ensure timely delivery
Flexible Quantity Quantities available from milligrams to ton

pGlu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

pGlu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala is a derivative of FGL, a peptide known for its cognitive benefits. In this derivative, the first amino acid, glutamate (Glu), in the original FGL sequence forms a cyclic structure known as pyroglutamate (pGlu). This modification is thought to enhance the peptide's stability and potentially its biological activity. The sequence alteration aims to retain or improve the therapeutic effects associated with FGL, such as enhancing memory function and rescuing cognitive impairments.

Category

Peptide Inhibitors

Catalog number

BAT-016514

Molecular Formula

C71H114N20O24

Molecular Weight

1631.78

pGlu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala

Specification

IUPAC Name

(2S,5S,8S,11S,17S,20S,23S,26S)-23-(2-amino-2-oxoethyl)-17,20-bis(3-amino-3-oxopropyl)-5,11-bis(4-aminobutyl)-26-((3S,6S,9S,12S,15S)-6-(4-hydroxybenzyl)-3,9,12-triisopropyl-15-methyl-1,4,7,10,13-pentaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14-pentaazahexadecan-16-amido)-8-(hydroxymethyl)-2-methyl-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazanonacosanedioic acid

Synonyms

FGL; Glp-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala-OH; L-Pyroglutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-L-alanine

Purity

≥95%

Sequence

pEVYVVAENQQGKSKA

Storage

Store at 2-8 °C

Solubility

Soluble in Water

InChI

InChI=1S/C71H114N20O24/c1-33(2)55(91-70(113)57(35(5)6)90-66(109)46(29-38-15-17-39(93)18-16-38)87-69(112)56(34(3)4)89-64(107)43-21-25-52(97)80-43)68(111)78-36(7)58(101)82-45(22-26-54(99)100)63(106)86-47(30-51(76)96)65(108)85-44(20-24-50(75)95)62(105)84-42(19-23-49(74)94)59(102)77-31-53(98)81-40(13-9-11-27-72)61(104)88-48(32-92)67(110)83-41(14-10-12-28-73)60(103)79-37(8)71(114)115/h15-18,33-37,40-48,55-57,92-93H,9-14,19-32,72-73H2,1-8H3,(H2,74,94)(H2,75,95)(H2,76,96)(H,77,102)(H,78,111)(H,79,103)(H,80,97)(H,81,98)(H,82,101)(H,83,110)(H,84,105)(H,85,108)(H,86,106)(H,87,112)(H,88,104)(H,89,107)(H,90,109)(H,91,113)(H,99,100)(H,114,115)/t36-,37-,40-,41-,42-,43-,44-,45-,46-,47-,48-,55-,56-,57-/m0/s1

InChI Key

BWONRBLTPRQBGA-RBXNGMIHSA-N